Prostate Cancer From Bench to Bedside


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Prostate Cancer: From Bench to Bedside


InTeOpP | 2011 | ISBN: 9533073316 9789533073316 | 527 pages | PDF | 28 MB


This textbook highlights many of the exciting discoveries made in the diagnosis and treatment of prostate cancer over the past decade. The book provides a comprehensive and state-of-the art review of the signaling pathways and genetic alterations essential in prostate cancer.
The book provides an essential resource for healthcare professionals and scientists dedicated to this field.

This textbook is dedicated to the efforts and advances made by our scientific community, realizing we have much to learn in striving to some day in the not too distant future cure this disease particularly among those with an aggressive tumor biology.

Contents
Preface
Part 1 Introduction
1 Prostate Cancer: Essential Diagnostic and Therapeutic Considerations
Part 2 Methods in Cancer Biology
2 Effective Methodologies for Statistical Inference on Microarray Studies
3 Prostate Cancer, the Long Search for Etiologic and Therapeutic Factors: Dietary Supplementation Avoiding Invasive Treatment
4 Advanced Models for Target Validation a Drug Discovery in Prostate Cancer
Part 3 Signaling Pathways
5 Signalling Pathways and Gene Expression Profiles in Prostate Cancer
6 Clinical Relevance of Circulating Nucleic Acids in Blood of Prostate Cancer Patients
7 TRP-Channels and Human Prostate Carcinogenesis
8 Epidermal Growth Factor Receptor (EGFR) Phosphorylation, Signaling and Trafficking in Prostate Cancer
9 Prostate Cancer Dephosphorylation Atlas
10 Modulation of One-Carbon Metabolism by B Vitamins: Implications for Transformation and Progression of Prostate Cancer
11 Integrins as Determinants of Genetic Susceptibility, Tumour Behaviour and Their Potential as Therapeutic Targets
12 Cytotoxic Endonucleases: New Targets for Prostate Cancer Chemotherapy
13 MAP Kinases and Prostate Cancer
Part 4 Drug Therapeutics Biological Agents
14 Evaluation of Phyllanthus, for Its Anti-Cancer Properties
15 Prostate Cancer Progression to Androgen Independent Disease: The Role of the Wntyp-Catenin Pathway
16 Prostate Carcinoma and Hot Flashes
17 Paradigm Shift in the Concept of Hormonal Milieu of Prostate Cancer
18 The Role of Cancer Stem Cells and MicroRNAs in Human Prostate Cancer
19 Zinc Supplementation and Prostate Cancer
20 The Role of Vitamin D in the Prevention and Treatment of Prostate Cancer
21 Highlights of Natural Products in Prostate Cancer Drug Discovery
22 The Potential Target Therapy of Prostate Cancer Stem Cells

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